6 Patterns > Acute Lung Injury Pattern > Subpatterns > w/ Granulomas

Acute Lung Injury w/ Granulomas

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Infection

Granulomatosis with Polyangiitis

Drug Reaction

Aspiration

Sample Signout

If no additional specific histologic features are identified, consider the following approach to signing the case out:

Acute and organizing lung injury with granulomas (see comment).

Comment:  Granulomas in the setting of acute lung injury are concerning for an infectious process and correlation with final culture studies is suggested prior to immune suppression/immune modulation. Other possibilities include aspiration, drug reaction, and granulomatosis with polyangiitis (GPA). Necrosis would favor infection over GPA. Correlation with serologic studies is suggested.